A working list of startups operating in the commonwealth, with ecosystem organizations available as separate views. Search, sort, filter — submit additions anytime.
20 of 1000
#Company↑SectorStageFoundedDescriptionRegion
001
Acumen Pharmaceuticals
Pharmaceutical company focused on developing treatments.
Biotech—1996Pharmaceutical company focused on developing treatments.CVL→
002
AgroSpheres
AgBiotech developing novel delivery system for safer, more effective pesticide delivery using Minicell bioparticle technology. 25+ employees.
BiotechSeries B2016AgBiotech developing novel delivery system for safer, more effective pesticide delivery using Minicell bioparticle technology. 25+ employees.CVL→
003
Block.one Spinout / Modular Genetics
Enzyme engineering for industrial bioprocessing; based in CRC Blacksburg.
BiotechSeries B2002Enzyme engineering for industrial bioprocessing; based in CRC Blacksburg.SWVA→
004
BUILT Biotechnologies
Regenerative DNA Assembly process for DNA synthesis and manufacturing-as-a-service.
BiotechSeed2021Regenerative DNA Assembly process for DNA synthesis and manufacturing-as-a-service.CVL→
005
Capra Biosciences
Biofilm-based biomanufacturing of sustainable renewable chemicals.
Biotech——Biofilm-based biomanufacturing of sustainable renewable chemicals.NoVA→
006
Cerillo, Llc
Cerillo, Llc is a Charlottesville, Virginia-based company.
Biotech—2016Cerillo, Llc is a Charlottesville, Virginia-based company.CVL→
007
Chorda Pharma
Pharmaceutical company listed in Virginia innovation portfolio.
Biotech——Pharmaceutical company listed in Virginia innovation portfolio.SWVA→
008
CvilleBioHub member: Diffuse Bio
Generative AI for protein and small-molecule design.
BiotechPre-seed2023Generative AI for protein and small-molecule design.CVL→
009
CytoRecovery
Develops advanced microfluidic technology to enable cell biologists to rapidly sort, enrich, and recover rare, homogeneous, viable cell subpopulations.
Biotech—2016Develops advanced microfluidic technology to enable cell biologists to rapidly sort, enrich, and recover rare, homogeneous, viable cell subpopulations.SWVA→
010
GPB Scientific
GPB Scientific is an automation of Cell Therapy Manufacturing.
Biotech——GPB Scientific is an automation of Cell Therapy Manufacturing.RVA→
011
HemoShear Therapeutics
Human-relevant disease models for rare metabolic diseases and pharma partnerships.
BiotechSeries B2008Human-relevant disease models for rare metabolic diseases and pharma partnerships.CVL→
012
Hyperion Bio
Single-cell sequencing instruments and reagents (UVA spinout).
BiotechSeed2022Single-cell sequencing instruments and reagents (UVA spinout).CVL→
Life sciences and regenerative medicine organization; included for ecosystem relevance.
BiotechSeries B—Life sciences and regenerative medicine organization; included for ecosystem relevance.HR→
015
Light Switch Bio
Seed-stage biotech spin-out from Massey Cancer Center. Drug delivery platforms.
Biotech——Seed-stage biotech spin-out from Massey Cancer Center. Drug delivery platforms.RVA→
016
Lumacyte
Lumacyte is a Virginia-based company focusing on rapid label-free single cell analysis.
Biotech——Lumacyte is a Virginia-based company focusing on rapid label-free single cell analysis.CVL→
017
Pleros Therapeutics
Biotechnology company founded in 2022 developing small molecule therapies for immunological disorders.
Biotech—2022Biotechnology company founded in 2022 developing small molecule therapies for immunological disorders.RVA→
018
Qentoros Inc
A biotech company harnessing the power of platelets to treat orthopedic disease in horses.
Biotech—2022A biotech company harnessing the power of platelets to treat orthopedic disease in horses.SWVA→
019
ReAlta Life Sciences
Peptide therapeutics targeting complement and innate immunity for inflammatory disease.
BiotechSeries B2018Peptide therapeutics targeting complement and innate immunity for inflammatory disease.HR→
020
Rivus Pharmaceuticals
Rivus Pharmaceuticals is dedicated to improving cardio-metabolic health by developing controlled metabolic accelerators (CMAs) that address the underlying metabolic risk factors for cardiovascular mortality and morbidity.
BiotechSeries B2019Rivus Pharmaceuticals is dedicated to improving cardio-metabolic health by developing controlled metabolic accelerators (CMAs) that address the underlying metabolic risk factors for cardiovascular mortality and morbidity.CVL→