A working list of startups operating in the commonwealth, with ecosystem organizations available as separate views. Search, sort, filter — submit additions anytime.
60 of 1000
#Company↑SectorStageFoundedDescriptionRegion
001
10Pearls
10Pearls is a mobile app and software development company that specializes in apps, web applications, and enterprise solutions.
Artificial Intelligence (AI)—200410Pearls is a mobile app and software development company that specializes in apps, web applications, and enterprise solutions.NoVA→
002
12New.AI
AI-Agents for Compliance, Procurement, Finance and Security.
Artificial Intelligence (AI)—2023AI-Agents for Compliance, Procurement, Finance and Security.NoVA→
003
Andesite AI
Andesite AI is a cybersecurity company that builds a product for human-AI collaboration in cyber defense.
Artificial Intelligence (AI)—2023Andesite AI is a cybersecurity company that builds a product for human-AI collaboration in cyber defense.NoVA→
004
AnswerThis
AnswerThis is an AI research assistant that helps researchers generate literature reviews, identify research gaps, and manage citations.
Artificial Intelligence (AI)—2023AnswerThis is an AI research assistant that helps researchers generate literature reviews, identify research gaps, and manage citations.RVA→
005
Artom
Artom is a company that offers technology services.
Artificial Intelligence (AI)—2022Artom is a company that offers technology services.RVA→
006
Ascender AI
Ascender AI is a startup that received angel funding with the goal of revolutionizing how people engage, discover, and absorb information.
Artificial Intelligence (AI)—2019Ascender AI is a startup that received angel funding with the goal of revolutionizing how people engage, discover, and absorb information.NoVA→
007
Autyvia
Autyvia develops AI-powered intelligence platform transforming enterprise data into unified, actionable insights.
Artificial Intelligence (AI)—2025Autyvia develops AI-powered intelligence platform transforming enterprise data into unified, actionable insights.NoVA→
008
Axios HQ
Axios HQ is AI-powered communication software that helps organizations in management information systems.
Artificial Intelligence (AI)—2021Axios HQ is AI-powered communication software that helps organizations in management information systems.NoVA→
009
Beside
Beside is an app that provides users with a dedicated second phone number for calls and texts.
Artificial Intelligence (AI)——Beside is an app that provides users with a dedicated second phone number for calls and texts.RVA→
010
BlackBoiler
BlackBoiler is a legal technology company that creates contract efficiency solutions for companies, law firms, and legal service providers.
Artificial Intelligence (AI)—2016BlackBoiler is a legal technology company that creates contract efficiency solutions for companies, law firms, and legal service providers.NoVA→
011
Bluesight
Bluesight is a medication intelligence company that utilizes AI and machine learning to reduce risks and solve supply chain inefficiencies.
Artificial Intelligence (AI)—2011Bluesight is a medication intelligence company that utilizes AI and machine learning to reduce risks and solve supply chain inefficiencies.NoVA→
012
Brandi
Brandi is an AI visibility and GEO platform that helps brand visibility in search engines like ChatGPT, Gemini, and Perplexity.
Artificial Intelligence (AI)—2025Brandi is an AI visibility and GEO platform that helps brand visibility in search engines like ChatGPT, Gemini, and Perplexity.NoVA→
013
BriefCatch
BriefCatch is a legal technology company that develops an AI-enhanced writing platform to help legal professionals refine legal documents.
Artificial Intelligence (AI)—2018BriefCatch is a legal technology company that develops an AI-enhanced writing platform to help legal professionals refine legal documents.NoVA→
014
Buckstop
The Urban Mining Company - Every retired asset has hidden value. We find it.
Artificial Intelligence (AI)—2025The Urban Mining Company - Every retired asset has hidden value. We find it.RVA→
015
Caju AI
Caju AI is an AI platform for enhancing customer engagement, workforce productivity, and business insights.
Artificial Intelligence (AI)—2023Caju AI is an AI platform for enhancing customer engagement, workforce productivity, and business insights.CVL→
016
Capital Defense Technologies
Capital Defense Technologies offers a defense AI tech platform for advanced military threats.
Artificial Intelligence (AI)—2025Capital Defense Technologies offers a defense AI tech platform for advanced military threats.NoVA→
017
Centripetal
Intelligence powered cybersecurity leader, operationalizing threat intelligence in real-time to protect enterprises from every known threat
Artificial Intelligence (AI)—2009Intelligence powered cybersecurity leader, operationalizing threat intelligence in real-time to protect enterprises from every known threatNoVA→
018
CLEATUS
CLEATUS is the all-in-one AI platform for GovCon. It automates discovery, capture, and proposals so any business can compete and win.
Artificial Intelligence (AI)—2025CLEATUS is the all-in-one AI platform for GovCon. It automates discovery, capture, and proposals so any business can compete and win.NoVA→
019
Dasion
Dasion provides crucial machine learning and artificial intelligence for healthcare.
Artificial Intelligence (AI)—2015Dasion provides crucial machine learning and artificial intelligence for healthcare.NoVA→
020
DataShapes
Provides hardware-agnostic, low SWaP RF AI software for real-time situational awareness and analytics anywhere, anytime it is needed.
Artificial Intelligence (AI)—2020Provides hardware-agnostic, low SWaP RF AI software for real-time situational awareness and analytics anywhere, anytime it is needed.CVL→
021
DEFCON AI
DEFCON AI optimize logistics and mobility decision-making through the use of advanced AI technology.
Artificial Intelligence (AI)—2022DEFCON AI optimize logistics and mobility decision-making through the use of advanced AI technology.NoVA→
022
Enabled Intelligence
Enabled Intelligence provides secure and accurate data labeling services.
Artificial Intelligence (AI)—2020Enabled Intelligence provides secure and accurate data labeling services.NoVA→
023
Entrokey Labs
Entrokey Labs offers quantum-resistant key generation, AI entropy calculator, and secure key synchronisation services.
Artificial Intelligence (AI)—2024Entrokey Labs offers quantum-resistant key generation, AI entropy calculator, and secure key synchronisation services.NoVA→
024
FACTIC
SaaS AI Predictive Analytics Platform for Past Insights and Future Simulation
Artificial Intelligence (AI)—2019SaaS AI Predictive Analytics Platform for Past Insights and Future SimulationVA→
025
Firetail
Unified AI & API security with a powerful platform that enables enterprises to protect the connections driving AI innovation.
Artificial Intelligence (AI)—2021Unified AI & API security with a powerful platform that enables enterprises to protect the connections driving AI innovation.NoVA→