A working list of startups operating in the commonwealth, with ecosystem organizations available as separate views. Search, sort, filter — submit additions anytime.
28 of 466
#Company↑SectorStageFoundedDescriptionRegion
001
Athela, LLC
Makes GermZAPP, a hand wash education and reward system apparatus that detects the user and encourages proper hand sanitizer use.
Health—2012Makes GermZAPP, a hand wash education and reward system apparatus that detects the user and encourages proper hand sanitizer use.SWVA→
002
Block.one Spinout / Modular Genetics
Enzyme engineering for industrial bioprocessing; based in CRC Blacksburg.
BiotechSeries B2002Enzyme engineering for industrial bioprocessing; based in CRC Blacksburg.SWVA→
003
Card Isle
On-demand greeting-card kiosks for grocery and floral retail.
CommerceSeries A2014On-demand greeting-card kiosks for grocery and floral retail.SWVA→
004
Chorda Pharma
Pharmaceutical company listed in Virginia innovation portfolio.
Biotech——Pharmaceutical company listed in Virginia innovation portfolio.SWVA→
005
Code One Training Solutions
Provides tech-driven courses in CPR and other lifesaving techniques to medical personnel and emergency responders.
Health—2007Provides tech-driven courses in CPR and other lifesaving techniques to medical personnel and emergency responders.SWVA→
006
Corvus Labs
A software company that specializes in building advanced intelligence and machine learning applications to augment human performance.
AI—2021A software company that specializes in building advanced intelligence and machine learning applications to augment human performance.SWVA→
007
CytoRecovery
Develops advanced microfluidic technology to enable cell biologists to rapidly sort, enrich, and recover rare, homogeneous, viable cell subpopulations.
Biotech—2016Develops advanced microfluidic technology to enable cell biologists to rapidly sort, enrich, and recover rare, homogeneous, viable cell subpopulations.SWVA→
008
Fermi Energy
Developing an EV battery technology to power electric vehicles using local materials, including one derived from coal.
Climate—2022Developing an EV battery technology to power electric vehicles using local materials, including one derived from coal.SWVA→
009
Floafers
Premium foam loafer brand designed in Roanoke.
ConsumerBootstrapped2017Premium foam loafer brand designed in Roanoke.SWVA→
010
FluxTeq
Manufactures low-cost heat flux sensors and thermal measurement systems for use in a variety of applications.
Hardware—2015Manufactures low-cost heat flux sensors and thermal measurement systems for use in a variety of applications.SWVA→
011
Heliponix (now Grōv)
Indoor automated growing appliance for households; VT grad founders.
AgtechSeries A2017Indoor automated growing appliance for households; VT grad founders.SWVA→
012
Helix Acoustics
A tech startup in the acoustics space, part of the RAMP cohort.
Hardware—2024A tech startup in the acoustics space, part of the RAMP cohort.SWVA→
A cloud-based data analytics platform designed exclusively for community banks and credit unions to provide actionable insights.
FintechSeries B2019A cloud-based data analytics platform designed exclusively for community banks and credit unions to provide actionable insights.SWVA→
015
Micronic Technologies
Sustainable water purification using mechanical-vapor compression.
ClimateSeries A2010Sustainable water purification using mechanical-vapor compression.SWVA→
016
Modea
Digital experience and product agency focused on healthcare systems.
HealthBootstrapped2008Digital experience and product agency focused on healthcare systems.SWVA→
017
Mountain Lake Software
Property management software for small lake associations and HOAs in the Mid-Atlantic.
SoftwareSeed2024Property management software for small lake associations and HOAs in the Mid-Atlantic.SWVA→
018
Ozmo
Tech-support content and tooling for telcos and OEMs; raised $25M.
SoftwareSeries B2013Tech-support content and tooling for telcos and OEMs; raised $25M.SWVA→
019
Pod Farms
Specializes in vertical hydroponic growing systems for controlled environment agriculture (CEA) farms.
Agtech—2017Specializes in vertical hydroponic growing systems for controlled environment agriculture (CEA) farms.SWVA→
020
PogoTec
Wearable camera/lifestyle accessories with magnetic mounting.
HardwareSeries A2013Wearable camera/lifestyle accessories with magnetic mounting.SWVA→
021
Qentoros Inc
A biotech company harnessing the power of platelets to treat orthopedic disease in horses.
Biotech—2022A biotech company harnessing the power of platelets to treat orthopedic disease in horses.SWVA→
022
RAMP
Roanoke-Blacksburg accelerator. Twelve-week program, hardware-friendly, partnered with Virginia Tech and Carilion Clinic.
AcceleratorsAccelerators2017Roanoke-Blacksburg accelerator. Twelve-week program, hardware-friendly, partnered with Virginia Tech and Carilion Clinic.SWVA→
023
Skyphos Technologies
A 3D printing service for rapid-prototyping and mass-fabrication for micro-devices used in Lab-on-a-Chip or Point of Care diagnostics.
Biotech—2017A 3D printing service for rapid-prototyping and mass-fabrication for micro-devices used in Lab-on-a-Chip or Point of Care diagnostics.SWVA→
024
The Molecular Sciences Software Institute
A nexus for science, education, and cooperation serving the worldwide community of computational molecular scientists.
Software—2016A nexus for science, education, and cooperation serving the worldwide community of computational molecular scientists.SWVA→
025
The Tiny Cargo Co.
Unlocks the potential of milk exosomes using proprietary technology to isolate exosomes from cows' milk in large quantities.
Biotech—2018Unlocks the potential of milk exosomes using proprietary technology to isolate exosomes from cows' milk in large quantities.SWVA→