A working list of startups operating in the commonwealth, with ecosystem organizations available as separate views. Search, sort, filter — submit additions anytime.
61 of 1274
#Company↑SectorStageFoundedDescriptionRegion
001
10Pearls
10Pearls is a mobile app and software development company that specializes in apps, web applications, and enterprise solutions.
Artificial Intelligence (AI)—200410Pearls is a mobile app and software development company that specializes in apps, web applications, and enterprise solutions.NoVA→
002
12New.AI
AI-Agents for Compliance, Procurement, Finance and Security.
Artificial Intelligence (AI)—2023AI-Agents for Compliance, Procurement, Finance and Security.NoVA→
003
Andesite AI
Andesite AI is a cybersecurity company that builds a product for human-AI collaboration in cyber defense.
Artificial Intelligence (AI)—2023Andesite AI is a cybersecurity company that builds a product for human-AI collaboration in cyber defense.NoVA→
004
Ascender AI
Ascender AI is a startup that received angel funding with the goal of revolutionizing how people engage, discover, and absorb information.
Artificial Intelligence (AI)—2019Ascender AI is a startup that received angel funding with the goal of revolutionizing how people engage, discover, and absorb information.NoVA→
005
Autyvia
Autyvia develops AI-powered intelligence platform transforming enterprise data into unified, actionable insights.
Artificial Intelligence (AI)—2025Autyvia develops AI-powered intelligence platform transforming enterprise data into unified, actionable insights.NoVA→
006
Axios HQ
Axios HQ is AI-powered communication software that helps organizations in management information systems.
Artificial Intelligence (AI)—2021Axios HQ is AI-powered communication software that helps organizations in management information systems.NoVA→
007
BlackBoiler
BlackBoiler is a legal technology company that creates contract efficiency solutions for companies, law firms, and legal service providers.
Artificial Intelligence (AI)—2016BlackBoiler is a legal technology company that creates contract efficiency solutions for companies, law firms, and legal service providers.NoVA→
008
Bluesight
Bluesight is a medication intelligence company that utilizes AI and machine learning to reduce risks and solve supply chain inefficiencies.
Artificial Intelligence (AI)—2011Bluesight is a medication intelligence company that utilizes AI and machine learning to reduce risks and solve supply chain inefficiencies.NoVA→
009
Brandi
Brandi is an AI visibility and GEO platform that helps brand visibility in search engines like ChatGPT, Gemini, and Perplexity.
Artificial Intelligence (AI)—2025Brandi is an AI visibility and GEO platform that helps brand visibility in search engines like ChatGPT, Gemini, and Perplexity.NoVA→
010
BriefCatch
BriefCatch is a legal technology company that develops an AI-enhanced writing platform to help legal professionals refine legal documents.
Artificial Intelligence (AI)—2018BriefCatch is a legal technology company that develops an AI-enhanced writing platform to help legal professionals refine legal documents.NoVA→
011
Capital Defense Technologies
Capital Defense Technologies offers a defense AI tech platform for advanced military threats.
Artificial Intelligence (AI)—2025Capital Defense Technologies offers a defense AI tech platform for advanced military threats.NoVA→
012
Centripetal
Intelligence powered cybersecurity leader, operationalizing threat intelligence in real-time to protect enterprises from every known threat
Artificial Intelligence (AI)—2009Intelligence powered cybersecurity leader, operationalizing threat intelligence in real-time to protect enterprises from every known threatNoVA→
013
CLEATUS
CLEATUS is the all-in-one AI platform for GovCon. It automates discovery, capture, and proposals so any business can compete and win.
Artificial Intelligence (AI)—2025CLEATUS is the all-in-one AI platform for GovCon. It automates discovery, capture, and proposals so any business can compete and win.NoVA→
014
Dasion
Dasion provides crucial machine learning and artificial intelligence for healthcare.
Artificial Intelligence (AI)—2015Dasion provides crucial machine learning and artificial intelligence for healthcare.NoVA→
015
DEFCON AI
DEFCON AI optimize logistics and mobility decision-making through the use of advanced AI technology.
Artificial Intelligence (AI)—2022DEFCON AI optimize logistics and mobility decision-making through the use of advanced AI technology.NoVA→
016
Enabled Intelligence
Enabled Intelligence provides secure and accurate data labeling services.
Artificial Intelligence (AI)—2020Enabled Intelligence provides secure and accurate data labeling services.NoVA→
017
Entrokey Labs
Entrokey Labs offers quantum-resistant key generation, AI entropy calculator, and secure key synchronisation services.
Artificial Intelligence (AI)—2024Entrokey Labs offers quantum-resistant key generation, AI entropy calculator, and secure key synchronisation services.NoVA→
018
Firetail
Unified AI & API security with a powerful platform that enables enterprises to protect the connections driving AI innovation.
Artificial Intelligence (AI)—2021Unified AI & API security with a powerful platform that enables enterprises to protect the connections driving AI innovation.NoVA→
019
Fixify
Fixify is an AI powered managed service provider for IT support.
Artificial Intelligence (AI)—2023Fixify is an AI powered managed service provider for IT support.NoVA→
020
Gallop.ai
Gallop makes booking your business travel a breeze.
Artificial Intelligence (AI)—2016Gallop makes booking your business travel a breeze.NoVA→
021
GenLogs
GenLogs is a freight intelligence company that offers truck carrier mapping services via AI-driven roadside sensors.
Artificial Intelligence (AI)—2023GenLogs is a freight intelligence company that offers truck carrier mapping services via AI-driven roadside sensors.NoVA→
022
GroupSense
GroupSense is a provider of cyber intelligence services filled with search tools, feeds, and briefings.
Artificial Intelligence (AI)—2014GroupSense is a provider of cyber intelligence services filled with search tools, feeds, and briefings.NoVA→
023
HelloGov
HelloGov is a full-stack AI/ML company, providing computer vision, NLP, and high quality training data for the public sector.
Artificial Intelligence (AI)—2016HelloGov is a full-stack AI/ML company, providing computer vision, NLP, and high quality training data for the public sector.NoVA→
024
IntelliGRC
IntelliGRC is a SaaS cybersecurity GRC solution for practitioners and service providers.
Artificial Intelligence (AI)—2025IntelliGRC is a SaaS cybersecurity GRC solution for practitioners and service providers.NoVA→
025
Jeeva
Jeeva optimizes and decentralizes clinical research to make innovation accessible to patients regardless of their location.
Artificial Intelligence (AI)—2019Jeeva optimizes and decentralizes clinical research to make innovation accessible to patients regardless of their location.NoVA→